Anadrol (Oxymetholone)

A profile on Oxymetholone, widely considered the most powerful oral mass-building steroid available, and its unique side effect profile.

Anadrol (Oxymetholone)

Anadrol (Oxymetholone), often called "A-Bombs", is the heavyweight champion of oral mass builders. If Dianabol is the breakfast of champions, Anadrol is the dinner of giants.

It was originally developed to treat anemia and muscle wasting diseases, which explains its potent ability to increase red blood cell count and appetite (though in high doses, it can paradoxically kill appetite).

Quick Specs

PropertyValue
Active CompoundOxymetholone
Half-Life8-9 Hours
Detection Time~8 Weeks
Anabolic/Androgenic Ratio320 : 45
Chemical FamilyDHT Derivative
AdministrationOral (Tablet)
HepatotoxicityVery High

Mechanism of Action

Anadrol is a Dihydrotestosterone (DHT) derivative. It possesses a 2-hydroxymethylene group, which is unique and responsible for its high anabolic activity. Like most orals, it is C-17 alpha-alkylated to survive liver metabolism.

The Estrogen Mystery: Unlike Dianabol, Anadrol does not aromatize into estrogen. It is a DHT derivative, and DHT cannot convert to estrogen. However, Anadrol causes significant water retention and gynecomastia. It is believed to activate estrogen receptors directly or modulate progesterone receptors, requiring a different approach to side effect management.

Pharmacokinetics & Dosing

Half-Life: ~9 Hours

  • Dosing: Standard practice is daily administration.
  • Dosage: Tablets usually come in 50mg.
    • Beginner: 25-50mg per day.
    • Advanced: 50-100mg per day.
    • Note: Clinical studies have shown that rising above 100mg/day provides diminishing returns on muscle growth while side effects skyrocket.

Primary Effects

1. Massive Size & Strength

Anadrol is the fastest way to add weight. Gains of 15-20 lbs in 4 weeks are not uncommon. It creates a massive, full look. Strength gains are explosive, often surpassing Dianabol.

2. Red Blood Cells (Pumps)

It drastically increases erythropoiesis (RBC production). This leads to insane vascularity and muscle pumps during training, sometimes to the point of being painful (e.g., lower back pumps).

3. Joint Lubrication

Many users report relief from joint pain while on Anadrol, likely due to water retention cushioning the joints during heavy lifting.

Side Effects & Harm Reduction

Estrogen Warning:

AI Won't Work: Because Anadrol does not convert to estrogen via aromatase, taking Arimidex (an aromatase inhibitor) will not stop Anadrol-induced gyno or water retention. You must use a SERM like Nolvadex (Tamoxifen) to block the receptor directly.

1. Hepatotoxicity

It is very liver toxic. Extended use can lead to liver cysts (Peliosis Hepatitis).

  • Management: Strict 4-6 week limit. No alcohol. High dose NAC/TUDCA.

2. Blood Pressure

The extreme water retention can spike BP into dangerous territory (hypertensive crisis).

  • Management: Daily BP monitoring is mandatory. Cardio and clean diet are essential.

3. Appetite Suppression

At higher doses or longer durations, Anadrol can cause nausea and kill appetite, making it counterproductive for bulking.

Tracking Anadrol

Using the Anabolic Tracker app:

  1. Inventory: Add Anadrol.
  2. Scheduling: Daily.
  3. Metrics: Track Blood Pressure and Weight daily. Track Appetite (1-10) to know when the compound is turning on you.
  4. Notes: Log any headaches or nosebleeds, which are signs of high BP.

Disclaimer:

This guide is for informational purposes only. Anadrol is a controlled substance. Misuse can lead to permanent health damage. Always consult with a medical professional.

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