Proviron (Mesterolone)
A profile on Mesterolone, a unique oral androgen used for libido, hardening, and SHBG management rather than raw muscle growth.
Proviron (Mesterolone)
Proviron (Mesterolone) is a unique anabolic steroid. Unlike almost every other AAS, it is not used to build muscle mass. It has very weak anabolic activity in muscle tissue.
Instead, Proviron is used as a "synergist" or support compound. It enhances the look of the physique (hardening), boosts libido, and makes other steroids more effective.
Quick Specs
| Property | Value |
|---|---|
| Active Compound | Mesterolone |
| Half-Life | ~12 Hours |
| Detection Time | ~5-6 Weeks |
| Anabolic/Androgenic Ratio | 100-150 : 30-40 (Effective: Androgenic only) |
| Chemical Family | DHT Derivative |
| Administration | Oral (Tablet) |
| Hepatotoxicity | Very Low (Not 17aa) |
Mechanism of Action
Proviron is a DHT derivative. Uniquely, it is not C-17 alpha-alkylated, but rather methylated at the 1-position. This protects it from liver metabolism enough to be oral, but it avoids the heavy liver toxicity of Winstrol or Dbol.
However, once in muscle tissue, Proviron is rapidly reduced into inactive metabolites by the 3-hydroxysteroid dehydrogenase enzyme. This is why it does not build muscle.
It has an extremely high affinity for SHBG (Sex Hormone Binding Globulin).
Primary Effects
1. SHBG Binding (The Multiplier Effect)
SHBG binds to testosterone, rendering it inactive. Proviron binds to SHBG more strongly than testosterone does. This displaces testosterone, leaving more "Free Testosterone" circulating in the blood to build muscle. Adding Proviron can make a 500mg Test cycle feel like 700mg.
2. Cosmetic Hardening
As a pure androgen, it promotes a hard, vascular, grainy look similar to Masteron.
3. Libido & Well-being
It is prescribed medically to treat low libido. On cycle, it prevents "Deca Dick" or libido crashes associated with other compounds.
4. Anti-Estrogenic Activity
Proviron has a mild affinity for the aromatase enzyme, preventing it from converting testosterone to estrogen. It acts as a very mild AI (Aromatase Inhibitor).
Side Effects & Harm Reduction
Proviron is generally considered one of the safest steroids regarding organ health, but it has specific androgenic risks.
1. Androgenic Side Effects
As essentially pure oral DHT, it can cause hair loss (MPB) rapidly in prone individuals. It can also cause acne and prostate enlargement.
2. Liver Toxicity
Unlike other orals, it is generally not hepatotoxic. It can be run for longer durations (10-12 weeks) safely alongside injectables.
3. Suppression
While mild, it is still suppressive to natural testosterone production at bodybuilding doses (50mg+). It should not be used as a "PCT" bridge.
Pharmacokinetics & Dosing
Half-Life: ~12 Hours
- Dosage: Standard bodybuilding dose is 25mg to 50mg per day. Some go up to 100mg, but returns diminish.
- Frequency: Usually split AM/PM.
Tracking Proviron
Using the Anabolic Tracker app:
- Inventory: Add Proviron.
- Scheduling: Twice Daily.
- Metrics: Track Libido and Mood. This is often the primary gauge of whether the compound is working for you.
- Notes: Record hair shedding if that is a concern for you.
Disclaimer:
This guide is for informational purposes only. Proviron is a controlled substance. Misuse can lead to health damage. Always consult with a medical professional.