AOD-9604

A profile on the "Anti-Obesity Drug," a modified fragment of HGH designed specifically to burn fat without affecting blood sugar or muscle growth.

AOD-9604

AOD-9604 is a modified form of amino acids 177-191 of the Human Growth Hormone (HGH) molecule.

Unlike full HGH, which causes muscle growth, insulin resistance, and water retention, AOD-9604 was developed solely for lipolysis (fat burning). It mimics the fat-reducing power of HGH but lacks the ability to bind to the HGH receptor that drives IGF-1 release. This makes it a pure fat-loss peptide with an excellent safety profile.

Quick Specs

PropertyValue
Active CompoundHGH Fragment 177-191 analog
Half-LifeShort (Functional effect hours)
MechanismLipolysis Stimulator / Lipogenesis Inhibitor
AdministrationSubcutaneous (SubQ)

Mechanism of Action

AOD-9604 works via two primary pathways:

  1. Stimulates Lipolysis: It triggers the release of fat from obese fat cells.
  2. Inhibits Lipogenesis: It prevents the accumulation of new fat in adipose tissue.

Crucially, it does not affect blood sugar or insulin levels (unlike HGH), making it safe for long-term use without the risk of diabetes or insulin resistance.

Pharmacokinetics & Dosing

Dosing Protocol

  • Dosage: 300mcg - 500mcg per day.
  • Frequency: Daily.
  • Timing:
    • Morning Fasted: Ideally 30-60 minutes before breakfast.
    • Fasting Window: For maximum effect, use it during a fasting window or before fasted cardio.

Comparison to HGH Frag 176-191

AOD-9604 is chemically similar to Frag 176-191 but has a tyrosine component added to stabilize the molecule. HGH Frag is notoriously fragile and degrades quickly; AOD-9604 is more stable and reliable.

Primary Effects

1. Pure Fat Loss

Targeted reduction of body fat, particularly stubborn abdominal fat.

2. Joint Health

Unexpectedly, clinical trials revealed that AOD-9604 may help repair cartilage and treat osteoarthritis, leading to its study for joint repair.

3. No HGH Side Effects

No water retention, no carpal tunnel, and no blood sugar spikes.

Side Effects & Harm Reduction

Safety Profile:

GRAS Status: AOD-9604 received "Generally Recognized As Safe" (GRAS) status in the USA for therapeutic use, highlighting its incredibly mild side effect profile compared to stimulants or hormonal agents.

1. Efficacy

It is not a miracle worker. It requires a caloric deficit to work effectively. It amplifies the fat loss of a diet; it does not overpower a bad diet.

Tracking AOD-9604

Using the Anabolic Tracker app:

  1. Inventory: Add AOD-9604.
  2. Scheduling: Daily (AM).
  3. Metrics: Track Waist Circumference and Body Fat %.

Disclaimer:

This guide is for informational purposes only. AOD-9604 is a research chemical.

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