Ibutamoren (MK-677)
A profile on the oral Growth Hormone Secretagogue, popularly used for appetite stimulation and sleep improvement without injections.
Ibutamoren (MK-677)
Ibutamoren (MK-677) is frequently categorized as a SARM, but it is actually a Growth Hormone Secretagogue (GHS). It mimics the hunger hormone Ghrelin.
It signals the pituitary gland to release more Growth Hormone (GH) and IGF-1. Unlike injecting HGH which shuts down natural production, MK-677 amplifies your natural pulses.
Quick Specs
| Property | Value |
|---|---|
| Active Compound | Ibutamoren |
| Half-Life | ~24 Hours |
| Mechanism | Ghrelin Mimetic |
| Administration | Oral (Capsule/Liquid) |
Mechanism of Action
It binds to the Ghrelin receptor. This does two things:
- Stimulates GH Release: Drastically increases endogenous GH and IGF-1 levels.
- Stimulates Appetite: Ghrelin is the "I'm hungry" hormone.
Pharmacokinetics & Dosing
Half-Life: ~24 Hours
- Frequency: Once Daily.
- Timing:
- Morning: If you want the appetite boost during the day.
- Pre-Bed: If the hunger makes you lethargic or if you want to sleep through the hunger pangs.
- Dosage: 10mg - 25mg per day.
Primary Effects
1. Appetite
The hunger on MK-677 can be voracious. It is an premier tool for bulking.
2. Recovery & Sleep
Increases REM sleep duration. Users report vivid dreams and feeling more rested.
3. Skin & Hair
Increased IGF-1 leads to clearer skin and faster hair/nail growth.
Side Effects & Harm Reduction
Diabetes Risk:
Blood Glucose: Like HGH, MK-677 raises blood sugar and can reduce insulin sensitivity. Monitor fasting blood glucose. If it creeps up, use a GDA (Glucose Disposal Agent) like Berberine or lower the carb intake.
1. Water Retention
Significant water weight gain is common in the first 2 weeks.
2. Lethargy
High insulin/blood sugar swings can cause daytime tiredness.
3. Anxiety
Ghrelin is linked to the stress response. Some users experience anxiety or "fight or flight" feelings.
Tracking MK-677
Using the Anabolic Tracker app:
- Inventory: Add Ibutamoren (MK-677).
- Scheduling: Daily.
- Metrics: Track Blood Glucose (Mandatory) and Weight.
- Notes: Log sleep quality.
Disclaimer:
This guide is for informational purposes only. MK-677 is a research chemical.