NAD+
A profile on Nicotinamide Adenine Dinucleotide, the "molecule of youth" essential for mitochondrial energy and DNA repair.
NAD+
NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in all living cells. It is essential for converting nutrients into ATP (cellular energy).
NAD+ levels decline significantly as we age (by age 50, you have half the NAD+ you had at age 20). This decline is linked to mitochondrial dysfunction, aging, and low energy. Injecting NAD+ is the most direct way to restore these levels.
Quick Specs
| Property | Value |
|---|---|
| Active Compound | NAD+ |
| Half-Life | Short (Rapidly metabolized) |
| Mechanism | Mitochondrial Coenzyme / Sirtuin Activator |
| Administration | Subcutaneous (SubQ) or IV |
Mechanism of Action
NAD+ works on two main fronts:
- Energy (ATP): It is the helper molecule that moves electrons during cellular respiration. Without it, mitochondria cannot produce energy.
- DNA Repair (Sirtuins): Sirtuins are "longevity genes" that repair DNA and regulate inflammation. They require NAD+ to function. Low NAD+ = inactive Sirtuins = accelerated aging.
Pharmacokinetics & Dosing
Dosing Protocol
- Dosage: 50mg - 100mg per injection (SubQ).
- Frequency: Daily or Every Other Day.
- Storage: NAD+ degrades easily. Keep refrigerated and away from light.
Administration Warning
NAD+ burns. Injecting it SubQ often causes a sharp burning sensation that lasts 5-10 minutes.
- IV Drip: Clinics offer high dose (500mg+) IV drips. These take 2-4 hours. Running it too fast causes severe nausea and chest pressure.
Primary Effects
1. Mental Clarity
Users report a "lifting of the veil." Brain fog dissipates, and focus sharpens.
2. Energy
Restores youthful energy levels, not in a jittery caffeine way, but in a "I don't need a nap" way.
3. Addiction Recovery
Clinically used to help reduce withdrawal cravings from alcohol and opioids by restoring neurochemistry.
Side Effects & Harm Reduction
The Flush:
Physiological Response: If you inject NAD+ too quickly (IV) or a high dose (SubQ), you may feel a wave of chest pressure, nausea, and stomach cramping. This is harmless but scary. It passes in minutes. Start low to assess tolerance.
1. Injection Pain
The burning is normal. Mixing with a small amount of bacteriostatic water or BPC-157 can help dilute the sting.
Tracking NAD+
Using the Anabolic Tracker app:
- Inventory: Add NAD+.
- Scheduling: Daily.
- Metrics: Track Energy Levels and Cognitive Function.
Disclaimer:
This guide is for informational purposes only. NAD+ is a supplement/research compound.