GW0742
A profile on "Super Cardarine," a newer PPAR agonist that may offer even greater metabolic benefits than GW-501516.
GW0742
GW0742 (often called "Super Cardarine") is a second-generation PPAR-delta agonist. It is structurally very similar to Cardarine (GW-501516) but is purported to be more potent.
Like Cardarine, it is not a SARM and is non-hormonal. It is used primarily for endurance enhancement and fat loss.
Quick Specs
| Property | Value |
|---|---|
| Active Compound | GW0742 |
| Half-Life | ~24 Hours |
| Detection Time | Unknown |
| Anabolic/Androgenic Ratio | N/A (Non-Hormonal) |
| Chemical Family | PPARδ Agonist |
| Administration | Oral |
Mechanism of Action
It activates PPAR-delta/beta receptors. This activation increases fatty acid oxidation in skeletal muscle and improves insulin sensitivity. Anecdotally, users report the endurance effects kick in faster with GW0742 than with standard Cardarine.
Pharmacokinetics & Dosing
Half-Life: ~24 Hours
- Frequency: Once daily.
- Dosage: 10mg to 20mg per day. Because it is considered more potent, some users start at 5mg.
Primary Effects
1. Rapid Fat Loss
Increases the body's ability to burn adipose tissue for fuel.
2. Instant Endurance
Similar to Cardarine, it drastically improves aerobic capacity.
3. Insulin Sensitivity
Improves how the body handles glucose, potentially aiding in nutrient partitioning.
Side Effects & Harm Reduction
Heart Size:
Cardiomegaly Risk: While Cardarine (GW-501516) is associated with cancer risks in rodents, GW0742 has shown in some limited rat studies to potentially increase heart size (cardiomegaly) at high doses. The safety profile is less established than Cardarine.
1. Non-Hormonal
No PCT required. No testosterone suppression.
2. Cancer Risk?
Because it shares the same mechanism as Cardarine, the theoretical risk of tumorigenesis likely applies, although specific long-term carcinogenicity studies on GW0742 are sparse.
Tracking GW0742
Using the Anabolic Tracker app:
- Inventory: Add GW0742.
- Scheduling: Daily.
- Metrics: Track Resting Heart Rate.
- Comparison: If you have used Cardarine before, use the notes section to compare efficacy.
Disclaimer:
This guide is for informational purposes only. GW0742 is an experimental research chemical.