PT-141 (Bremelanotide)
A profile on the only FDA-approved peptide for hypoactive sexual desire, effective for both men and women.
PT-141 (Bremelanotide)
PT-141 (Bremelanotide) is a synthetic peptide originally developed from Melanotan II. While Melanotan II causes tanning and arousal, scientists isolated the specific part of the molecule responsible for arousal to create PT-141.
It is unique because it works on the nervous system (hypothalamus) rather than the vascular system (like Viagra/Cialis). This means it can treat erectile dysfunction or low libido even when blood flow is not the issue.
Quick Specs
| Property | Value |
|---|---|
| Active Compound | Bremelanotide |
| Half-Life | Short (Effects last 6-24+ hours) |
| Mechanism | Melanocortin Agonist (MC3/MC4) |
| Administration | Subcutaneous (SubQ) |
Mechanism of Action
PT-141 binds to melanocortin receptors in the brain. It triggers the neurological signal for arousal.
- Men: Stronger erections and increased desire.
- Women: Increased blood flow and physical sensation.
Pharmacokinetics & Dosing
Dosing Protocol
Timing is Critical. It takes time to kick in.
- Dosage: 1mg - 2mg. (Start with 1mg).
- Timing: Inject 4 to 6 hours before planned sexual activity. It is not instant.
- Frequency: Do not use more than 8 times per month (max twice weekly) to avoid receptor desensitization.
Primary Effects
1. Libido Enhancement
It doesn't just enable performance; it increases the desire to perform.
2. Erectile Quality
Works synergistically with Cialis for refractory ED cases.
Side Effects & Harm Reduction
Nausea:
The Main Drawback: About 20-30% of users experience significant nausea roughly 30 minutes after injection.
- Tip: If you inject 4-6 hours early, the nausea usually subsides by the time the libido effects peak.
1. Flushing
Redness in the face and neck is common post-injection.
2. Blood Pressure
It causes a temporary spike in blood pressure. Do not use if you have uncontrolled hypertension.
Tracking PT-141
Using the Anabolic Tracker app:
- Inventory: Add PT-141.
- Scheduling: As Needed (Custom).
- Metrics: Track Libido and Side Effects (Nausea).
Disclaimer:
This guide is for informational purposes only. PT-141 is FDA approved as Vyleesi.