SR9011
A profile on SR9011, a Rev-Erb agonist designed to regulate circadian rhythm and metabolism, often considered a more bioavailable version of Stenabolic.
SR9011
SR9011 is a Rev-Erb agonist developed by Professor Thomas Burris at Scripps Research Institute. It is the "sister" compound to SR9009 (Stenabolic).
Like SR9009, it alters the body's circadian rhythm and metabolic rate. It is used to drastically increase endurance, reduce anxiety, and burn fat. It is not a SARM and is non-hormonal.
Quick Specs
| Property | Value |
|---|---|
| Active Compound | SR9011 |
| Half-Life | ~4 Hours |
| Detection Time | Unknown |
| Anabolic/Androgenic Ratio | N/A (Non-Hormonal) |
| Chemical Family | Rev-Erb Agonist |
| Administration | Oral (Poor bioavailability) / Injectable |
Mechanism of Action
SR9011 binds to Rev-Erb alpha and beta proteins. These proteins regulate the circadian clock (sleep/wake cycle) and lipid/glucose metabolism.
By agonizing these receptors, SR9011 increases basal metabolic rate (even at rest) and stimulates the production of new mitochondria (mitochondrial biogenesis).
Pharmacokinetics & Dosing
Half-Life: ~4 Hours
- The Bioavailability Issue: Like SR9009, oral bioavailability is extremely low (< 3%).
- Administration:
- Oral: Must be dosed 3-4 times daily (every 4 hours) to be effective. Sublingual administration helps.
- Injectable: Much more effective. Dosed once daily or pre-workout.
- Dosage: 10mg - 20mg per day.
Primary Effects
1. Endurance
Increases VO2 max and running distance in animal models by 50%+. Users report similar effects to Cardarine.
2. Fat Loss
Increases energy expenditure. It works even while sedentary, though exercise amplifies the effect.
3. Circadian Rhythm
Can help regulate sleep patterns and keep you alert during the day.
Side Effects & Harm Reduction
Sleep Disturbance:
Timing Matters: Because it affects the circadian clock, taking SR9011 too late in the evening can cause insomnia or wakefulness ("revving up" the system when it should be winding down).
1. Non-Hormonal
No PCT required.
2. Anxiety?
Unlike some stimulants, Rev-Erb agonists actually show anxiolytic (anti-anxiety) properties in studies.
Tracking SR9011
Using the Anabolic Tracker app:
- Inventory: Add SR9011.
- Scheduling: 3x Daily (if oral) or Daily (if injectable).
- Metrics: Track Sleep Quality. Adjust dosing times if sleep quality drops.
Disclaimer:
This guide is for informational purposes only. SR9011 is a research chemical.