CJC-1295 w/ DAC

A profile on the long-acting GHRH analog, known for creating a continuous "bleed" of Growth Hormone levels.

CJC-1295 w/ DAC

CJC-1295 is a synthetic analog of Growth Hormone Releasing Hormone (GHRH). It is typically found in two forms: with DAC (Drug Affinity Complex) and without DAC (often called Mod GRF 1-29).

This profile covers CJC-1295 with DAC, which binds to plasma albumin and remains active in the body for days, creating a constant elevation of GH levels.

Quick Specs

PropertyValue
Active CompoundCJC-1295 + DAC
Half-Life~6-8 Days
MechanismGHRH Agonist
AdministrationSubcutaneous (SubQ)

Mechanism of Action

Normally, GHRH has a half-life of minutes. The addition of the DAC allows the peptide to bind to albumin in the blood, protecting it from degradation.

This results in a continuous stimulation of the pituitary gland to release Growth Hormone, creating a "GH bleed" (steady state) rather than the natural pulsatile release.

Pharmacokinetics & Dosing

Half-Life: ~6-8 Days

  • Frequency: Once or Twice Weekly.
  • Dosage: 1mg to 2mg per week total.
  • Stacking: Often stacked with Ipamorelin or MK-677 (GH Secretagogues) to maximize the pulse and the baseline.

Primary Effects

1. Elevated IGF-1

Significant and sustained increase in IGF-1 levels, driving muscle growth and fat loss.

2. Sleep & Recovery

Deep sleep is enhanced, though the constant "bleed" of GH can sometimes disrupt natural circadian rhythms compared to pulsatile peptides (like Mod GRF).

Side Effects & Harm Reduction

The GH Bleed:

Natural vs Synthetic: Some experts argue that a constant "bleed" of GH is unnatural and desensitizes the pituitary gland, making it less effective over time. For this reason, many prefer Mod GRF 1-29 (No DAC) injected multiple times a day to mimic natural pulses.

1. Flushing

A "head rush" or warm flushing sensation immediately after injection is common.

2. Water Retention

Can cause significant water hold, similar to HGH.

Tracking CJC-1295

Using the Anabolic Tracker app:

  1. Inventory: Add CJC-1295 w/ DAC.
  2. Scheduling: Twice Weekly (e.g., Mon/Thu).
  3. Metrics: Track Water Retention via body weight fluctuations.

Disclaimer:

This guide is for informational purposes only. CJC-1295 is a research chemical.

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